Brian Gladnick MD

Research Experience

2018 – Present | W.B. Carrell Memorial Clinic
Design and conduct of clinical research projects in the field of hip and knee arthroplasty

 

2017 – 2018 | Georgetown University School of Medicine, Research Mentor
Mentored Georgetown medical students in the design and completion of a graduation research project in the field of clinical orthopaedic research    

 

2017 – 2018 | Department of Orthopaedic Surgery, Virginia Hospital Center/OrthoVirginia
Designed and conducted clinical research projects in the field of hip and knee arthroplasty

 

2015 – 2016 | OrthoCarolina Research Institute, OrthoCarolina
Fellow in Adult Hip and Knee Reconstruction.

Designed and conducted clinical research in the field of revision total joint replacement, specifically evaluating outcomes after head/liner exchange through a direct anterior approach, and mid-term results following complex acetabular reconstruction with a custom triflange component

 

2010 – 2015 | Department of Orthopaedic Surgery, Hospital for Special Surgery
Resident in Orthopaedic Surgery.

Designed and completed multiple research projects involving both clinical and basic science, with a focus in adult reconstruction and total joint replacement and native knee biomechanics

 

2008 − 2009 | Department of Orthopaedic Surgery, Hospital for Special Surgery
Graduate Research Assistant.

Completed a one-year research position, in the field of metabolic bone diseases, between the third and fourth academic years of medical school

 

2006 | Department of Orthopaedic Surgery, Hospital for Special Surgery
Graduate Research Assistant.

Completed a ten-week research position during the summer after the first year of medical school, investigating fracture healing in a rodent femoral model

 

2003 − 2005 | Department of Biological Sciences, University of Delaware
Undergraduate Research Assistant.

Completed two and a half years of undergraduate research in the field of molecular biology and gene expression, which culminated in the publication of a Senior Thesis at the time of graduation


Publications and Submitted Works

Peer-Reviewed Scientific Articles

  1. Kapilow JM, Gladnick BP, Anderson LA, Peters Jr PC, Masonis JL. Acetabular exposure is enhanced with self-retaining retractors during direct anterior total hip arthroplasty. 2019 [Submitted to Hip International].
     
  2. Cochrane NH, Pachter CS, Garfinkel JH, Gladnick TB, Gladnick EP, Romness DW, Gladnick BP. Patient perceptions of antibiotic prophylaxis for dental procedures after total joint arthroplasty. 2019 [Submitted to J Orthop].
     
  3. Pachter CS, Garfinkel JH, Cochrane NH, Romness DW, Gladnick BP. Smoking is a risk factor for wound complications with 2-octyl cyanoacrylate mesh tape closure after direct anterior hip arthroplasty. 2019 [Accepted to: Adv Skin Wound Care].
     
  4. Garfinkel JH, Gladnick BP, Pachter CS, Cochrane NH. Romness DW. Perioperative factors associated with increased length of stay after revision of metal-on-metal total hip arthroplasty. J Orthop. 2019 Jan 17; 16(2): 109-112.
     
  5. Pachter CS, Garfinkel JH, Romness DW, Gladnick BP. Radiographic calibration with a prosthetic femoral head allows accurate pre-operative templating for total hip arthroplasty. Orthopedics. 2019 Mar 26: 1-4.
     
  6. Gladnick BP, Fehring KA, Odum SM, Christie MJ, DeBoer DK, Fehring TK. Mid-term survivorship after revision total hip arthroplasty with a custom triflange acetabular component. J Arthroplasty. 2018 Feb;33(2):500-504.
     
  7. Garfinkel JH, Gladnick BP, Roland N, Romness DW. Increased Incidence of Bleeding and Wound Complications with Factor-Xa Inhibitors after Total Joint Arthroplasty. J Arthroplasty. 2018 Feb;33(2):533-536.
     
  8. Gladnick BP, Schreiber JJ, Ishmael CR, Bjerke-Kroll B, Cunningham ME. Assessment of vertebral curves using the manual Post-It technique. Clin Spine Surg. 2017 Apr;30(3):E148-E151.
     
  9. Ruzbarsky JJ, Gladnick BP, Dodwell E. Diagnosing septic arthritis in the synovial white cell count "gray zone". HSSJ. 2016 Jul;12(2):190-2.
     
  10. Gladnick BP, Boorman-Padgett J, Stone K, Kent RN, Cross MB, Mayman DJ, Pearle AD, Imhauser CW. Primary and Coupled Motions of the Native Knee in Response to Applied Varus and Valgus Load. Knee. 2016 Jun;23(3):387-92.
     
  11. Khamaisy S, Zuiderbaan HA, Thein R, Gladnick BP, Pearle AD. Coronal tibiofemoral subluxation in knee osteoarthritis. Skeletal Radio. 2016 Jan;45(1):57-61.
     
  12. Khamaisy S, Gladnick BP, Nam D, Reinhardt KR, Heyse TJ, Pearle AD. Lower limb alignment control: Is it more challenging in lateral compared to medial unicondylar knee arthroplasty? Knee. 2015 Sep;22(4)347-50.
     
  13. Gladnick BP, Nam D, Khamaisy S, Paul S, Pearle AD. Onlay tibial implants appear to provide superior clinical results in robotic unicompartmental knee arthroplasty. HSSJ. 2015 Feb;11(1):43-9.
     
  14. Esposito CI, Gladnick BP, Lee Y, Lyman S, Wright TM, Mayman DJ, Padgett DE. Cup position alone does not predict risk of dislocation after hip arthroplasty. J Arthroplasty. 2015 Jan;30(1):109-113.
     
  15. Bjerke-Kroll B, Sculco P, McLawhorn A, Christ A, Gladnick BP, Mayman D. The increased total cost associated with post-operative drains in total hip and knee replacement. J Arthroplasty. 2014 May; 29(5): 895-899.
     
  16. Peralta-Morelo JV, Gladnick BP, Lee Y, Ferrer AV, Lyman S, Della Valle AG. Patellofemoral crepitation and clunk following modern, fixed-bearing total knee arthroplasty. J Arthroplasty. 2014 Mar; 29(3): 535-40.
     
  17. King BR, Gladnick BP, Lee YY, Lyman S, Della Valle AG. Range of motion and function are not affected by increased post constraint in patients undergoing posterior stabilized total knee arthroplasty. Knee. 2014 Jan; 21(1): 194-8.
     
  18. Nam D, Khamaisy S, Gladnick BP, Paul S, Pearl AD. Is tibiofemoral subluxation correctable in unicompartmental knee arthroplasty? J Arthroplasty. 2013 Oct; 28(9): 1575-9.
     
  19. Rebolledo BJ, Gladnick BP, Unnanuntana A, Nguyen JT, Kepler CK, Lane JM. Comparison of unipedicular and bipedicular balloon kyphoplasty for treatment of osteoporotic vertebral compression fractures: a prospective randomized study. Bone Joint J. 2013 Mar; 95-B(3): 401-6.
     
  20. Donnelly E, Meredith DS, Nguyen JT, Gladnick BP, Rebolledo BJ, Shaffer AD, Lorich DG, Lane JM, Boskey AL.  Reduced cortical bone compositional heterogeneity with bisphosphonate treatment in postmenopausal women with intertrochanteric and subtrochanteric fractures.  J Bone Miner Res. 2012 Mar;27(3):672-8.
     
  21. Unnanuntana A, Rebolledo BJ, Gladnick BP, Nguyen JT, Sculco TP, Cornell CN, Lane JM.  Does Vitamin D status affect the attainment of in-hospital functional milestones after total hip arthroplasty?  J Arthroplasty.  2012 Mar; 27(3): 482-9.

Peer-Reviewed Review Articles

  1. Gladnick BP, Masonis JL. Repair of the released conjoint tendon after direct anterior total hip arthroplasty: description of a novel technique. Orthopedics. 2018 Jul; 41(4):e583-e586.  
     
  2. Gladnick BP, Della Valle AG. Patellofemoral crepitation and clunk complicating posterior stabilized total knee arthroplasty. Am J Orthop. 2014; 43(10):458-464.
     
  3. Unnanuntana A, Gladnick BP, Donnelly E, Lane JM. Current concepts review: The assessment of fracture risk.  J Bone Joint Surg Am. 2010 Mar; 92(3):743-53.

Textbook Chapters

  1. Unnanuntana A, Gladnick BP, Lane JM. Osteoporosis and the Aging Spine: Diagnosis and Treatment. In: The Comprehensive Treatment of the Aging Spine: Minimally Invasive and Advanced Techniques. (1): 68-74. Yue JJ, Guyer R, Johnson JP, Khoo LT, Hochschuler S. Saunders (Elsevier); Philadelphia, PA, 2011.
     
  2. Unnanuntana A, Gladnick BP, McArthur B, McCarthy M, Lane JM.  Metabolic Bone Diseases. In: Orthopaedic Surgery: Principles of Diagnosis and Treatment. (1): 97 – 115. Wiesel B, Sankar W, Delahay J, Wiesel S. LLW; Philadelphia, PA, 2011.
     
  3. Unnanuntana A, Miki R, Gladnick BP, Sherman PJ, Madore GR, Lane JM.  Metabolic Bone Disorders of the Spine.  In: Rothman-Simeone: The Spine. (6): 2; 1571-1595.  Herkowitz HN, Garfin SR, Eismont FJ, Bell GR, Balderston RA. Saunders (Elsevier); Philadelphia, PA, 2011.

Abstracts, Podium Presentations, and Poster Presentations

  1. Pachter CS, Garfinkel JH, Romness DW, Gladnick BP.  Radiographic calibration with a prosthetic femoral head allows accurate pre-operative templating for total hip arthroplasty. [Abstract and E-Poster Presentation #53]. In: Virginia Orthopaedic Society Annual Meeting; April 20-22, 2018; White Sulphur Springs, WV.
     
  2. Garfinkel JH, Gladnick BP, Roland N, Pachter CS, Romness DW. Presence of abductor injury predicts increased length of stay after revision of metal-on-metal total hip arthroplasty. [Abstract and E-Poster Presentation #57]. In: Virginia Orthopaedic Society Annual Meeting; April 20-22, 2018; White Sulphur Springs, WV.
     
  3. Garfinkel JH, Gladnick BP, Roland N, Romness DW. Aspirin versus Factor-Xa Inhibitors: Thromboembolic Prophylaxis after Joint Replacement. [Abstract and Podium Presentation #2625]. In: American Academy of Orthopaedic Surgeons; March 6-10, 2018; New Orleans, LA.
     
  4. Gladnick BP, Odum SM, Masonis JL. Results of Head/Liner Exchange with the Direct Anterior Approach. [Abstract and E-Poster Presentation] In: Eastern Orthopaedic Association; October 18-21, 2017; Miami FL.
     
  5. Gladnick BP, Fehring KA, Odum SM, Christie MJ, DeBoer DK, Fehring TK. Mid-term survivorship after revision total hip arthroplasty with a triflange acetabular component. [Abstract and Poster Presentation # 129]. In: American Association of Hip and Knee Surgeons; November 10-13, 2016; Dallas TX.
     
  6. Gladnick BP, Fehring KA, Odum SM, Christie MJ, DeBoer DK, Fehring TK. Mid-term survivorship after revision total hip arthroplasty with a triflange acetabular component. [Abstract and Poster Presentation]. In: Closed Meeting of the Hip Society; October 27-29, 2016; Boston, MA.
     
  7. Gladnick BP, Imhauser C, Stone K, Kia M, Lipman J, Cross MB, Jerabek SA, Mayman DJ, Pearle AD. Coronal plane stability of the native knee during mid-flexion [Abstract and Poster Presentation #2053]. In: American Association of Hip and Knee Surgeons; November 7-9, 2014; Dallas TX.
     
  8. Peralta-Morelo JV, Gladnick BP, Lee Y, Lyman S, Della Valle AG. Factors affecting patellofemoral crepitation and clunk following total knee arthroplasty [Abstract and Poster Presentation #P190]. In: American Academy of Orthopaedic Surgeons; March 11-15, 2014; New Orleans, LA.
     
  9. Gladnick BP, Nam D, Khamaisy S, Paul S, Pearle AD. Inlay versus onlay tibial implants in robotic unicondylar knee arthroplasty [Abstract and Podium Presentation]. In: International Society for Technology in Arthroplasty; October 17-19, 2013; Palm Beach, FL.
     
  10. Gladnick BP, Khamaisy S, Nam D, Reinhardt K, Pearle AD. Lower limb alignment control: Is it more challenging in lateral versus medial unicondylar knee arthroplasty? [Abstract and Podium Presentation]. In: International Society for Technology in Arthroplasty; October 17-19, 2013; Palm Beach, FL.
     
  11. Rebolledo BJ, Donnelly E, Lorich DG, Gladnick BP, Unnanuntana A, Boskey AL, Lane JM. Altered bone quality in bisphosphonate-related femoral fractures of post-menopausal women [Abstract and Podium Presentation #38]. In: Orthopaedic Trauma Association; October 13-16, 2010; Baltimore, MD.
     
  12. Donnelly E, Meredith DS, Nguyen JT, Gladnick BP, Unnanuntana A, Lane JM, Boskey AL.  Mean bone tissue composition, but not heterogeneity, is consistent across iliac crest and trochanteric sites [Abstract].  In: Orthopaedic Research Society; March 6-9, 2010; New Orleans, LA.
     
  13. Rebolledo BJ, Unnanuntana A, Gladnick BP, Kepler CK, Grant EC, Lane JM.  A comparative study of four vertebral augmentation techniques for treatment of vertebral compression fractures [Abstract].  In: Orthopaedic Research Society; March 6-9, 2010; New Orleans, LA.
     
  14. Gladnick BP, Donnelly E, Lorich DG, Unnanuntana A, DiCarlo E, Doty S, Boskey AL, Lane JM.  The effects of long-term bisphosphonate use on bone quality [Abstract and Podium Presentation #339]. In: American Academy of Orthopaedic Surgeons; March 10-13, 2010; New Orleans, LA.
     
  15. Unnanuntana A, North T, Gladnick BP, Rodney A, Lane JM.  Do acute fractures influence the anabolic activities of teriparatide? [Abstract and Podium Presentation #244].  In: American Academy of Orthopaedic Surgeons; March 10-13, 2010; New Orleans, LA.
     
  16. Unnanuntana A, Gladnick BP, Cornell CN, Sculco TP, Lane JM.  Does serum 25-hydroxyvitamin D affect the physical therapy milestones in total hip arthroplasty patients? [Abstract and Poster Presentation #MO0379].  In: American Society for Bone and Mineral Research; September 11-15, 2009; Denver, CO.
     
  17. Gladnick BP, Unnanuntana A, Kepler CK, Lane JM.  Radiographic outcomes with unipedicular versus bipedicular balloon kyphoplasty: a prospective randomized controlled study [Abstract and Poster Presentation #SU0389].  In: American Society for Bone and Mineral Research; September 11-15, 2009; Denver, CO.
     
  18. Donnelly E, Gladnick BP, Lane JM, Boskey AL.  Bisphosphonate treatment reduces cortical compositional heterogeneity in postmenopausal women with femoral fractures [Abstract and Podium Presentation #1107].  In: American Society for Bone and Mineral Research; September 11-15, 2009; Denver, CO.

Undergraduate Senior Thesis

  1. Gladnick BP.  Maximal induction of brain creatine kinase by AP2 also requires factor NF-Y.  University of Delaware; Newark, DE, May 2005.
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